Human Ribonucleoside-Diphosphate Reductase Subunit M2 B, RRM2B ELISA Kit, 15*96T Protein Post-translational Modification targeting them for rapid degradation

targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression

The encoded protein is only active when it is phosphorylated

Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene

this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity

the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains

Human Ribonucleoside-Diphosphate Reductase Subunit M2 B, RRM2B ELISA Kit, 15*96T Protein Post-translational Modification targeting them for rapid degradation